Bioanalytical capabilities of micellar liquid chromatography |
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| Institution: | Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, United States;Thermo Fisher Scientific, Winsford, United Kingdom;University of Idaho, Moscow, ID, United States;Oak Ridge National Laboratory, Oak Ridge, TN, United States |
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| Abstract: | Micellar liquid chromatography (MLC) offers numerous advantages over other high-performance liquid chromatographic methods in bioanalytical applications, allowing improvements in simultaneous separation of ionic and non-ionic compounds, faster analysis, and higher detection sensitivity and selectivity. In addition, MLC can facilitate the estimation of the hydrophobic character of biologically active molecules in structure—activity relationships. |
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