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A practical, one-pot synthesis of sulfonylated pyridines
Authors:Maloney Kevin M  Kuethe Jeffrey T  Linn Kathleen
Institution:Department of Process Research, Merck & Co., Inc., Rahway, New Jersey 07065, United States. kevin_maloney@merck.com
Abstract:A concise and efficient one-pot synthesis of functionalized sulfonylated pyridines via an S(N)Ar reaction of readily available pyridines and sodium sulfinate salts in the presence of tetrabutylammonium chloride is presented.
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