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Synthesis and Biological Activities of Diosgenin-Triazole Conjugates with a 1,3-Dipolar Cycloaddition Reaction
Authors:Liao  Jun  Liao  Guochao  Gao  Yun  Chai  Xiaoyun  Wu  Qiuye  Zhao  Qingjie
Affiliation:1.Department of Biochemistry and Molecular Biology, College of Basic Medical Sciences, Second Military Medical University, 200433, Shanghai, P. R. China
;2.Department of Organic Chemistry, College of Pharmacy, Second Military Medical University, 200433, Shanghai, P. R. China
;3.International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, 510006, Guangzhou, P. R. China
;4.College of Pharmacy, Zhejiang Chinese Medical University, 311400, Hangzhou, P. R. China
;
Abstract:Chemistry of Natural Compounds - A novel series of diosgenin-triazole conjugates (10a–d, 11a–c, 12a–c, 13a–c) was designed and synthesized as antifungal agents by using a...
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