| 基于杯[4]芳烃的手性识别* |
| |
| 引用本文： | 卿光焱 刘顺英 何永炳. 基于杯[4]芳烃的手性识别*[J]. 化学进展, 2008, 20(12): 1933-1944 |
| |
| 作者姓名： | 卿光焱 刘顺英 何永炳 |
| |
| 作者单位： | (1. 武汉大学化学与分子科学学院 武汉 430072；
2. 华东师范大学新药创制先进技术研究院 上海 200062) |
| |
| 摘 要： | 手性杯芳烃是一类重要的主体化合物，在手性识别、对映体分离和不对称催化等方面有着广泛的用途。[4]芳烃引其稳定的构象和易于修饰的特点，成为研究最为广泛的杯芳烃分子，其中大量的文献报道了能够用于对映体识别和检测的手性[4]芳烃。在手性识别的研究中，荧光、紫外和核磁是3中最常见的研究方法，本文根据这3种方法进行分类，综述了近年来以杯[4]芳烃为分子骨架的手性受体的合成及其在手性识别中的应用。最后对手性[4]芳烃的发展前景作了展望。
|
| 关 键 词： | 手性识别 杯[4]芳烃 对映体检测 |
| 收稿时间： | 2008-01-21 |
| 修稿时间： | 2008-03-14 |
Chiral Recognition Based on Calix[4]arene |
| |
| Qing GuangyanLiu Shunying He Yongbing. Chiral Recognition Based on Calix[4]arene[J]. Progress in Chemistry, 2008, 20(12): 1933-1944 |
| |
| Authors: | Qing GuangyanLiu Shunying He Yongbing |
| |
| Affiliation: | (1. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China; 2. Advanced Research Center of NBIC Integrated Drug Discovery and Development, East China Normal University, Shanghai, 200062, China) |
| |
| Abstract: | Chiral calixarenes are a class of important host compounds and have wide applications in chiral recognition, enantiomer separation and asymmetrical catalysis. calix[4]arena is investigated most widely due to its stable conformation and easy derivatization. Among them lots of works reported the chiral calix[4]arenas can be used in enantiometric recognition and dectection. Fluorescence, UV-vis and NMR are the most common methods in the research of chiral recognition. Acording to these methods, the latest research progress in the synthesis of chiral receptors based on calix[4]arenas and theri applications in the chiral recognition are summerized. The prospect of chiral calix[4]arena is also discussed. |
| |
| Keywords: | chiral recognition calix[4]arene enantiomeric detection |
| 本文献已被 维普 万方数据 等数据库收录！ |
| 点击此处可从《化学进展》浏览原始摘要信息 |
|
点击此处可从《化学进展》下载全文 |
