| Investigation and Application of Polarographic Catalytic Wave of Oxygen Reduction Caused by Mefenamic Acid |
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| 作者姓名： | 宋俊峰 过玮 亢晓峰 胡荫华 |
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| 作者单位： | Department of Chemistry. Northwest University，Xi'an 710069，RPC，Department of Chemistry. Northwest University，Xi'an 710069，RPC，Department of Chemistry. Northwest University，Xi'an 710069，RPC，Department of Chemistry. Northwest University，Xi'an 710069，RPC |
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| 摘 要： | The polarographic catalytic wave of oxygen reduction caused by mefenamic acid (MA) with redox properties was reported in this paper. The electrochemical process of the catalytic wave was proposed that the superoxide anion O(?) was generated polarographically and the dismutation of the O(?) was catalyzed by MA to reproduce O_2 and H_2O_2. This explained chemically the scavenging of the O_2~- by MA im biomedical area. Based on the catalytic wave, a new method for the determination of MA by single-sweep polarography was developed.
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Investigation and Application of Polarographic Catalytic Wave of Oxygen Reduction Caused by Mefenamic Acid |
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| SONG Jun-Feng GUO Wei,KANG Xiao-Feng HU Yin-Hua.Investigation and Application of Polarographic Catalytic Wave of Oxygen Reduction Caused by Mefenamic Acid[J].Science in China(Chemistry),1993(8). |
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| Authors: | SONG Jun-Feng GUO Wei KANG Xiao-Feng HU Yin-Hua |
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| Abstract: | The polarographic catalytic wave of oxygen reduction caused by mefenamic acid (MA) with redox properties was reported in this paper. The electrochemical process of the catalytic wave was proposed that the superoxide anion O(?) was generated polarographically and the dismutation of the O(?) was catalyzed by MA to reproduce O_2 and H_2O_2. This explained chemically the scavenging of the O_2~- by MA im biomedical area. Based on the catalytic wave, a new method for the determination of MA by single-sweep polarography was developed. |
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| Keywords: | mefenamic acid[61-68-7] pharmaceutical chemistry superoxide anion O_2~+[11062-77-4] dismutation polarographic catalytic wave |
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