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Metal induced selectivity in phosphate ion binding in E9 DNase |
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| Authors: | van den Bremer Ewald T J Keeble Anthony H Kleanthous Colin Heck Albert J R |
| Affiliation: | Department of Biomolecular Mass Spectrometry, Bijvoet Center for Biomolecular Research & Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands. |
| Abstract: | Mass spectrometric and calorimetric data reveal that phosphate ion binding to the active site of colicin E9 DNase is delicately regulated by concomitant binding of specific transition metal ions. |
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