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氧化锆基质HPLC 柱填料研究进展*
引用本文:敦惠娟,赵惠敏,陈立仁.氧化锆基质HPLC 柱填料研究进展*[J].化学进展,2005,17(6):0-1122.
作者姓名:敦惠娟  赵惠敏  陈立仁
作者单位:1. 河北师范大学化学学院,石家庄,050016
2. 中国科学院兰州化学物理研究所,兰州,730000
基金项目:国家自然科学基金(No.20375045),河北师范大学博士基金(No.L2004B09)资助
摘    要:氧化锆具有很好的化学、机械和热稳定性,适合于碱性物质,特别是生物大分子的分离。氧化锆的色谱性能与硅胶形成很好的互补,具有广阔的应用前景。本文对氧化锆微球表面修饰方法及在色谱分析中的应用进行了综述分析。分析表明氧化锆是性能优异的色谱基质填料。

关 键 词:高效液相色谱(HPLC)  色谱填料  氧化锆
文章编号:1005-281X(2005)06-1116-07
收稿时间:2004-11
修稿时间:2005-01

Modification and Application of Zirconia2Based Packings in HPLC Separations
Dun Huijuan,Zhao Huimin,Chen Liren.Modification and Application of Zirconia2Based Packings in HPLC Separations[J].Progress in Chemistry,2005,17(6):0-1122.
Authors:Dun Huijuan  Zhao Huimin  Chen Liren
Institution:Department of Chemistry, Hebei Normal University, Shijiazhuang 050016, China;Lanzhou Institute of Chemical Physics, The Chinese Academy of Sciences, Lanzhou 730000, China
Abstract:Zirconia exhibits excellent chemical,thermal and mechanical stability.Recently,there has been an increasing importance in application of zirconia support for their good basic and bioanalytic suitability.Zirconia shows different selectivity from silica and it enriches the power of high performance liquid chromatography(HPLC).In this review,the various modifications of zirconia packings,their application in HPLC separations are outlined.It has been found that zirconia is a promising HPLC packing support.
Keywords:high performance liquid chromatography(HPLC)  packings  zirconia
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