Synthesis,spectroscopic and crystal structure analysis of 2-(4-fluorobenzyl)-6-(4-methoxyphenyl)imidazo[2,1-b][1,3,4]thiadiazole and its morpholinomethyl derivative |
| |
| Authors: | Afshan Banu D.E. Vasundhara Ravi S. Lamani I.A.M. Khazi Noor Shahina Begum |
| |
| Affiliation: | 1. Department of Chemistry, Bangalore University, Bangalore 560 001, India;2. Department of Chemistry, Karnatak University, Dharwad 580 003, India |
| |
| Abstract: | The preparation of 2-(4-fluorobenzyl)-6-(4-methoxyphenyl)-5-morpholin-1-ylmethyl imidazo[2,1-b][1,3,4]thiadiazole via the intermediate 2-(4-fluorobenzyl)-6-(4-methoxyphenyl)Imidazo[2,1-b][1,3,4] thiadiazole is described. Elemental analysis, IR spectrum, 1H NMR and X-ray crystal structure analyses were carried out to determine the compositions and molecular structures of the two compounds. The crystal packing exhibits intermolecular C–H?O, C–H?N, C–H?F and π–π stacking interactions leading to the formation of the supramolecular network. |
| |
| Keywords: | Imidazo[2,1-b] 1,3,4-thiadiazoles Crystal structure Morpholinomethyl derivative Weak interactions: C–H…O, C–H…N, C–H…F and π–π stacking |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
