食品及环境样品中双酚类物质的前处理及检测方法研究进展

双酚类物质作为一种环境内分泌干扰物，广泛存在于食品包装材料及环境介质中，对生态环境造成污染，也对人体健康产生一定危害。双酚残留是目前重要的食品安全问题，检测食品和环境样品中的双酚类物质的含量对人体健康具有重要的意义。由于残留目标物浓度通常较低，且实际样品存在基质干扰，因此需经一定的样品前处理，并结合仪器分析方法，提高检测效率，增强分析灵敏度与可靠性。常用的前处理分析方法主要有液液萃取、微波辅助萃取、固相萃取、固相微萃取、基质分散固相萃取、QuEChERS等，常用仪器分析方法包括液相色谱法、气相色谱法、毛细管电泳法、酶联免疫吸附测定法、生物传感器法等。该文综述了食品及环境样品中双酚类物质的样品前处理及仪器分析方法，为双酚类化合物的残留监测提供了参考依据。

Research progress on pretreatment and detection of bisphenols in food and environmental samples

Bisphenols, which are environmental endocrine disruptors, are widely found in food packaging materials and the environment, polluting the ecological environment and inducing harm to human health. Bisphenol residues constitute an important food safety problem at present. Hence, detecting the bisphenol content in food and environmental samples is of great significance for protecting human health. Because of the low concentration and matrix interference, a combination of sample pretreatment and instrumental analysis is imperative for improving the detection efficiency and enhancing the analytical sensitivity and reliability. Common pretreatment and analysis methods mainly include liquid-liquid extraction, microwave-assisted extraction, solid-phase extraction, solid-phase microextraction, matrix-dispersive solid-phase extraction, and QuEChERS. Common instrumental analysis methods include liquid chromatography, gas chromatography, capillary electrophoresis, immunoassays, and biosensors. In this paper, various methods for sample pretreatment and instrumental analysis of bisphenols in food and environmental samples are reviewed, with the aim of providing a reference for the residue monitoring of bisphenols.