Synthesis of conjugates of 2′,3′-dideoxynucleoside-5′-monophosphates with α-amino acids |
| |
| Authors: | E V Zhernosek S V Kvach L A Eroshevskaya E N Kalinichenko A I Zinchenko |
| |
| Institution: | (1) Institute of Bioorganic Chemistry, National Academy of Sciences of Belarus’, 220141, Belarus’, Minsk, ul. Kuprevicha, 5/2;(2) Institute of Microbiology, National Academy of Sciences of Belarus’, 220141, Belarus’, Minsk, ul. Kuprevicha, 2 |
| |
| Abstract: | Previously undescribed conjugates of 2′,3′-dideoxyuridine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (5) and 2′,3′-dideoxycytidine-5′-monophosphate-(L)-methoxytryptophylphosphoramidate (7) were isolated by a chemical enzymatic method in order to study their pharmacological properties and to prepare new medicinal
preparations based on them.
__________
Translated from Khimiya Prirodnykh Soedinenii, No. 2, pp. 173–175, March–April, 2006. |
| |
| Keywords: | nucleotides nucleosides 2′ 3′ -dideoxycytidine 2′ 3′ -dideoxyuridine conjugates L-tryptophan cytidinedeaminase nucleosidephosphotransferase Escherichia coli Erwinia herbicola |
| 本文献已被 SpringerLink 等数据库收录！ |
|
