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Total synthesis of unguisin A |
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| Authors: | Hunter Luke Chung Jonathan H |
| Institution: | School of Chemistry, The University of Sydney, NSW 2006, Australia. |
| Abstract: | The first synthesis of the γ-aminobutyric acid (GABA)-containing cyclic heptapeptide unguisin A is reported, confirming the structure of this natural product. Macrocyclization of a flexible GABA-containing linear precursor is found to proceed rapidly and in good yield. |
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