Mutated variant of Candida antarctica lipase B in (S)-selective dynamic kinetic resolution of secondary alcohols |
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| Authors: | Engström Karin Vallin Michaela Syrén Per-Olof Hult Karl Bäckvall Jan-E |
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| Affiliation: | Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University, SE-106 91, Stockholm, Sweden. |
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| Abstract: | An (S)-selective dynamic kinetic resolution of secondary alcohols, employing a mutated variant of Candida antarctica lipase B (CalB) gave products in 84-88% yield and in 90-97% ee. |
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