| Synthesis, Crystal Structure and DNA Binding Studies of a Nickel（II） Complex with 2-Aminomethylbenzimidazole and Demethylcantharate |
| |
| 作者姓名： | LI Shi-Kun LIN Qiu-Yue LV Tian-Xi WANG Yan-Jun CHEN Dong |
| |
| 作者单位： | [1]Zhejiang Key Laboratory for Reaction Chemistry on Solid Surfaces, Zhejiang Normal University, Jinhua 321004, China [2]College of Chemical andLife Science, Zhejiang Normal University, Jinhua 321004, China |
| |
| 基金项目： | Supported by the Natural Science Foundation of Zhejiang Province （Y407301） |
| |
| 摘 要： | A new mixed-ligand nickel(Ⅱ) complex, Ni(L)(DCA)(H2O)]·2H2O (L = C8H9N3, 2-aminomethyl-benzimidazole, DCA2- = 7-oxabicyclo2,2,1]heptane-2,3-dicarboxylate, demethylcantharate, C8H8O5), has been synthesized and characterized. The structure of the complex was determined by single-crystal X-ray diffraction. It is of monoclinic system, space group P21/c with a = 7.7211(7), b = 12.0799(12), c = 19.7867(19), β = 100.390(6)°, V = 1815.2(3) nm3, Dc = 1.625 g·cm-3, Ζ = 4, F(000) = 928, R = 0.0314 and wR = 0.0822. In addition, the interaction between the complex and DNA was studied by means of fluorescence spectra and viscosity. The results indicate that the complex binds to DNA by the mode of partial intercalation with the Stern-Volmer constants Ksv of 3.81 × 104 mol·L-1.
|
| 关 键 词： | DNA作用 镍（Ⅱ） 晶体结构 合成 混合配体 苯并咪唑 射线衍射 单斜晶系 |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
