| Studies on the energy transfer system of terbium-norfloxacin chelate and its interaction with serum albumins |
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| 作者姓名： | XU Yan SHEN Han-Xi |
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| 作者单位： | XU，Yan SHEN，Han-Xi Department of Chemistry，Nankai University，Tianjin 300071，ChinaHUANG，Han-Guo Department of Chemistry Engineering，Hebei Institute of Technology，Tangshan，Hebei 063009，China |
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| 基金项目： | Project supported by the National Natural Science Foundation of China. |
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| 摘 要： | The energy absorbed by norfloxacin could be transferred to terbium(Ⅲ) through chela-tion of norfloxacin with terbium(Ⅲ),then the characteristic fluorescence emission could be observed.The interaction of serum albumins with norfloxacin have been investigated in this paper.The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(Ⅲ).But,BSA could not.It was shown that the binding properties of norfloxacin to HSA and BSA were totally different.
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| 关 键 词： | Norfloxacin terbium(Ⅲ) energy transfer HSA BSA |
Studies on the energy transfer system of terbium-norfloxacin chelate and its interaction with serum albumins |
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| XU,Yan SHEN,Han-Xi.Studies on the energy transfer system of terbium-norfloxacin chelate and its interaction with serum albumins[J].Chinese Journal of Chemistry,1997,15(2):138-143. |
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| Authors: | XU Yan SHEN Han-Xi |
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| Institution: | XU,Yan SHEN,Han-Xi Department of Chemistry,Nankai University,Tianjin 300071,ChinaHUANG,Han-Guo Department of Chemistry Engineering,Hebei Institute of Technology,Tangshan,Hebei 063009,China |
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| Abstract: | The energy absorbed by norfloxacin could be transferred to terbium(III) through chelation of norfloxacin with terbium(III), then the characteristic fluorescence emission could be observed. The interaction of serum albumins with norfloxacin have been investigated in this paper. The results showed that HSA could inhibit the energy transfer between norfloxacin and terbium(III). But, BSA could not. It was shown that the binding properties of norfloxacin to HSA and BSA were totally different. |
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| Keywords: | Norfloxacin terbium(III) energy transfer HAS BSA |
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