Crystal structures of bis(quinidinium) molybdate hydrate and quinidinium chloride hydrate: The question of the stable conformation of quinidine

Anx-ray structural study of QndH⁺]₂MoO ₄ ^2– ]H₂O (1) and QndH⁺]Cl^–H₂O (2), where Qnd = quinidine, was conducted. The structures have an ionic structure, and the ions are joined by hydrogen bonds into chains (1) and layers (2). Quinidinium cations protonated at the quinuclidine N atom have a conformation with agauche position of the N atom and OH group (as in neutral quinidine) corresponding to the local, and not the global, minimum of the calculated conformational energy.A. N. Nesmeyanov Institute of Organoelemental Compounds, Russian Academy of Sciences, 117813 Moscow. Translated from Izvestiya Akademii Nauk, Seriya Khimicheskaya, No. 5, pp. 1073–1078, May, 1992.