Chiral bonded packings for liquid chromatography: Preparation and evaluation of N-acylated aminoacid packings based on aminopropylated silica gel |
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| Authors: | J. N. Akanya D. R. Taylor |
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| Affiliation: | (1) Chemistry Department, Federal University of Technology, P.O. Box 656, Minna, Nigeria;(2) Chemistry Department, University of Manchester, Institute of Science and Technology, M60 1QD Manchester, UK |
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| Abstract: | Summary N-Protected single amino acid residues have been chemically bound to aminopropylated silica gel to give chiral HPLC column packings. Surface coverages have been determined by both elemental and aminoacid analyses. In addition, the nature of the surface-bound groups has been studied by reflectance fourier transform infrared (FTIR) spectroscopy. The resolution of a range of racemic mixtures has been achieved using the column packings. |
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| Keywords: | Column liquid chromatography Chiral bonded phases Enantiomer separations Amino acid esters |
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