Synthesis,structure, and biologic activity of products of reactions between dinitrodichlorobenzofuroxane and aminopyrimidines in aqueous dimethyl sulfoxide |
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Authors: | I V Galkina L M Yusupova A T Gubaidullin V I Galkin |
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Abstract: | Reactions of 4,6-dinitro-5,7-dichlorobenzofuroxane with substituted pyrimidines in aqueous DMSO proceed through an intermediate formation of 5-hydroxy-4,6-dinitro-7-chlorobenzofuroxane owing to the hydrolysis of one of the chlorine atoms with the subsequent formation of pyrimidine salts exhibiting a high biologic action. |
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