Leucosceptrine--a novel sesterterpene with prolylendopeptidase inhibitory activity from Leucosceptrum canum |
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| Authors: | Choudhary Muhammad Iqbal Ranjit Rosa Atta-Ur-Rahman Atta-Ur-Rahman Shrestha Tirtha Maiya Yasin Amsha Parvez Masood |
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| Affiliation: | H. E. J. Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan. hej@cyber.net.pk |
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| Abstract: | A novel sesterterpene, leucosceptrine, was isolated from the medicinal plant Leucosceptrum canum from Nepal. The structure was determined by single-crystal X-ray diffraction and spectroscopic techniques. The biosynthesis of leucosceptrine (1) is proposed here. Leucosceptrine (1) exhibited prolylendopeptidase inhibitory activity. |
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