New pyridocarbazole alkaloids from Strychnos nitida |
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| Authors: | Wei Li Gui-Hua Tang Lin Chen Ya-Qi Tang You-Kai Xu |
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| Institution: | 1. School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China;2. Key Laboratory of Tropical Plant Resource and Sustainable Use, Xishuangbanna Tropical Botanical Garden, Chinese Academy of Sciences, Menglun, China |
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| Abstract: | Phytochemical investigation of Strychnos nitida has led to the isolation of three new racemic pyridocarbazole alkaloids, (±)-stritidas A-C (1–3) and three known monoterpenoid indole alkaloids (4–6). Compounds 2 and 3 represent the first examples of pyridocarbazole alkaloids featuring an N-2-hydroxyethyl moiety. Their structures were determined by combined spectroscopic data (MS, UV, IR and NMR) and chemical methods. |
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| Keywords: | Strychnos nitida pridocarbazole alkaloids monoterpenoid indole alkaloids |
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