Isolation and structure elucidation of a new compound from the fungus Aspergillus flavipes PJ03-11 |
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| Authors: | Fang Liu Gang Chen Li-hua Zhang Bing Liu Shaofei Chen Huiming Hua |
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| Affiliation: | 1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, China;2. Key Laboratory of Structure-Based Drug Design and Discovery, Shenyang Pharmaceutical University, Ministry of Education, Shenyang, China;3. Institute?of?Materia?Medica, Chinese Academy of Medical Sciences &4. Peking Union Medical College, Beijing, China;5. Life science and Environmental Science Research Center, Harbin University of Commerce, Harbin, China |
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| Abstract: | A new diphenyl ether 3-methylpentyl-2, 4-dichloroasterrate (2), along with a known diphenyl ether butyl 2, 4-dichloroasterrate (1) were isolated from the metabolites of a wetland fungus Aspergillus flavipes. PJ03-11. The structures of 1 and 2 were determined by extensive NMR and HR–ESI–MS experiments. Compounds 1 and 2 showed weak cytotoxic activity, but both of them showed no antimicrobial activity. |
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| Keywords: | Soil fungus Aspergillus diphenyl ether cytotoxic activity |
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