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Simple and efficient approach for synthesis of hydrazones from carbonyl compounds and hydrazides catalyzed by meglumine
Authors:Mo Zhang  Ze-Ren Shang  Xiao-Tang Li  Jia-Nan Zhang  Yong Wang  Kang Li
Institution:College of Chemistry and Material Science, Hebei Normal University, Shijiazhuang, China
Abstract:A simple, environmentally benign protocol for synthesis of hydrazones from carbonyl compounds and hydrazides has been developed in the presence of meglumine in aqueous-ethanol media at room temperature. The salient features of the present protocol are mild reaction conditions, short reaction time, high yields, operational simplicity, metal-free, applicability toward large-scale synthesis, and biodegradable and inexpensive catalyst.
Keywords:Carbonyl compounds  green and sustainable chemistry  hydrazides  hydrazones  meglumine  metal-free
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