Review: Separation and Pharmacology of Chiral Compounds in Traditional Chinese Medicine |
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Authors: | Xiong-Fei Wang Ke Sun Yue-Zhu Ding |
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Affiliation: | School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, China |
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Abstract: | More than 60% commonly used pharmaceutical active ingredients are chiral compounds. Developing more effective and safe chiral compounds has become a focus in the pharmaceutical industry. Chiral compounds widely exist in traditional Chinese medicine and include alkaloids, flavonoids, volatile oils, and amino acids. The characterization of chiral compounds used in traditional Chinese medicine remains limited. Here, the characterization of chiral compounds commonly used in traditional Chinese medicine is reviewed focusing upon their separation and pharmacology. |
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Keywords: | Chiral compound chiral separation high-performance liquid chromatography pharmacology traditional Chinese medicine |
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