Two new phenolic constituents from the root bark of Morus alba L. and their cardioprotective activity |
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| Authors: | Yan-gang Cao Xiao-ke Zheng Fang-fang Yang Fang Li Man Qi Yan-li Zhang |
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| Institution: | 1. School of Pharmacy, Heilongjiang University of Chinese Medicine, Harbin, P.R. China;2. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, P.R. China;3. School of Pharmacy, Henan University of Chinese Medicine, Zhengzhou, P.R. China |
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| Abstract: | A new biphenyl-furocoumarin, named morescoumarin A (1), and a new prenylated flavanone, named morflavanone A (2) were isolated from the root bark of Morus alba L., together with four known compounds (3–6). Their structures were determined by extensive spectroscopic analyses and comparison with literature data. The cardioprotective effects of these compounds against doxorubicin-induced cell death were evaluated by MTT method. |
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| Keywords: | Morus alba L Moraceae phenolic constituents cardioprotective effect |
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