Synthesis and antimicrobial evaluation of some novel dithiolane,thiophene, coumarin,and 2-pyridone derivatives |
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| Authors: | Mahmoud R. Mahmoud Amira T. Ali Yasmeen M. Ali |
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| Affiliation: | Faculty of Science, Department of Chemistry, Ain Shams University, Abbassia, Cairo, Egypt |
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| Abstract: | Novel 2-cyano-N-[1-(naphtha-2-yl)ethylidene] acetohydrazide 1 was utilized as key intermediate for the synthesis of some new dithiolane, thiophene, coumarin, 2-pyridone, and other related products containing a hydrazide moiety. Newly synthesized compounds were characterized by elemental analyses and spectral data (IR, 1H NMR and mass spectra). The antimicrobial activity of the synthesized compounds was evaluated. |
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| Keywords: | Cyanoacetohydrazide dithiolane derivatives hydrazide-hydrazone thiophene derivatives |
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