A new bischromanone from the stems of Semecarpus caudata |
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| Authors: | Phu H. Dang Tinh T. Nguyen Tho H. Le Hai X. Nguyen Mai T. T. Nguyen |
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| Affiliation: | 1. Faculty of Chemistry, VNUHCM–University of Science, Ho Chi Minh City, Vietnam;2. Cancer Research Laboratory, Vietnam National University, Ho Chi Minh City, Vietnam |
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| Abstract: | From an CHCl3-soluble fraction of the stems of Semecarpus caudata, one new bischromanone named semecarpanone (1), together with 5 known flavonoids (2–6) were isolated. Their structures were elucidated based on interpretation of spectroscopic data. The stereo-configuration of 1 was identified based on the calculated and experimental coupling constants. Compounds 4–6 showed potent tyrosinase inhibitory activity with the IC50 values ranging from 15.0 to 76.3 μM. |
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| Keywords: | Semecarpus caudata Anacardiaceae bischromanone tyrosinase inhibitory |
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