15-deoxy-isoxeniolide-A,new diterpenoid from a bornean soft coral,Xenia sp. |
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| Authors: | Chin-Soon Phan Takashi Kamada Kazushi Kobayashi Toshiyuki Hamada |
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| Affiliation: | 1. Laboratory of Natural Products Chemistry, Institute for Tropical Biology and Conservation, Universiti Malaysia Sabah, Sabah, Malaysia;2. Graduate School of Science and Engineering, Kagoshima University, Kagoshima, Japan |
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| Abstract: | A new xenicane diterpenoid, 15-deoxy-isoxeniolide-A (1) along with four known compounds 9-deoxy-isoxeniolide-A (2), isoxeniolide-A (3), xeniolide-A (4) and coraxeniolide-B (5) were isolated from the Bornean soft coral Xenia sp. The structures of these metabolites were elucidated on the basis of spectral analysis, NMR and HRESIMS. Compound 5 showed cytotoxic activity against ATL cell line, S1T. |
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| Keywords: | Soft coral Xenia sp. xenicane diterpene adult T-cell leukaemia S1T |
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