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Overview of the synthetic routes to tadalafil and its analogues |
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| Authors: | Moustafa A Gouda |
| Institution: | 1. Department of Chemistry, Faculty of Science and Arts, Taibah University, Ulla, Kingdom of Saudi Arabia;2. Department of Chemistry, Faculty of Science, Mansoura University, Mansoura, Egyptdr_mostafa_chem@yahoo.com |
| Abstract: | The biological and medicinal properties of tadalafil and its analogues have prompted enormous research aimed at developing synthetic routes to these heterocyclic analogues. This review focuses on the chemical properties associated with this system. |
| Keywords: | Cialis Pictet–Spengler reaction pyrido[3 4-b]indole-1 4-dione tadalafil β-carboline" target="_blank">tetrahydro-β-carboline |