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Acid-catalyzed intramolecular cyclization of N-(4,4-diethoxybutyl)sulfonamides as a novel approach to the 1-sulfonyl-2-arylpyrrolidines |
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| Authors: | Almir S Gazizov Andrey V Smolobochkin Ekaterina A Anikina Julia K Voronina Alexander R Burilov Michail A Pudovik |
| Institution: | 1. A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russian Federationagazizov@iopc.ru;3. A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Kazan, Russian Federation;4. Kazan National Research Technological University, Kazan, Russian Federation |
| Abstract: | Herein we report our studies on the acid-catalyzed cyclisation of N-(4,4-diethoxybutyl)sulfonamides at the presence of polyatomic phenols as an efficient one-pot approach to the synthesis of 1-sulfonyl-2-arylpyrrolidines from the acyclic precursors. |
| Keywords: | Acetal cyclization pyrrolidine resorcinol sulfonamide |