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A new cyclic dipeptide from cultures of Coprinus plicatilis
Authors:Jiang-Yuan Zhao  Jian-Hai Ding  Zheng-Hui Li  Tao Feng  Hong-Bin Zhang
Affiliation:1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, PR China27343904@qq.com;3. Engineering and Technology Research Center of Liupanshan Resources, College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, PR China;4. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, PR China;5. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, PR China
Abstract:Three cyclic dipeptides (1–3), including one new compound (1) were isolated from cultures of the basidiomycetes Coprinus plicatilis. Their structures were elucidated by spectroscopic methods, including extensive 2D NMR techniques. At the same time, all compounds were tested for their cytotoxicities against five human cancer cell lines.
Keywords:Coprinus plicatilis  cyclic dipeptide  cytotoxicity
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