A new cyclic dipeptide from cultures of Coprinus plicatilis |
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Authors: | Jiang-Yuan Zhao Jian-Hai Ding Zheng-Hui Li Tao Feng Hong-Bin Zhang |
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Affiliation: | 1. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, PR China27343904@qq.com;3. Engineering and Technology Research Center of Liupanshan Resources, College of Chemistry and Chemical Engineering, Ningxia Normal University, Guyuan, PR China;4. School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan, PR China;5. Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, Yunnan University, Kunming, PR China |
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Abstract: | Three cyclic dipeptides (1–3), including one new compound (1) were isolated from cultures of the basidiomycetes Coprinus plicatilis. Their structures were elucidated by spectroscopic methods, including extensive 2D NMR techniques. At the same time, all compounds were tested for their cytotoxicities against five human cancer cell lines. |
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Keywords: | Coprinus plicatilis cyclic dipeptide cytotoxicity |
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