New triterpenoid saponins from the steaming treated roots of Panax notoginseng |
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| Authors: | Cheng-Zhen Gu Yi-Jun Qiao Dong Wang Hong-Tao Zhu Chong-Ren Yang Min Xu |
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| Affiliation: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, People’s Republic of China;2. College of Life Science, Fujian Agriculture and Forestry University, Fuzhou, People’s Republic of China |
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| Abstract: | Further phytochemical investigation of the steaming treated roots of Panax notoginseng (Araliaceae) led to the identification of two new dammarane-type triterpenoid saponins, notoginsenoside SP20 (1) and SP21 (2). In addition, a pair of new phenolic glycosides (3a and 3b) was also isolated together with two known compounds. Their structures were elucidated by HRESIMS, 1D- and 2D-NMR spectra. Compounds 1 and 2 showed no in vitro cytotoxicity against five human cancer cell lines (HL-60, SMMC-7712, A-549, MCF-9 and SW480). |
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| Keywords: | Panax notoginseng Araliaceae triterpenoid saponins |
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