The effects of selected phytochemicals on biofilm formed by five methicillin-resistant Staphylococcus aureus |
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| Authors: | Barbara Kot Kamila Wierzchowska Agata Grużewska Dzmitry Lohinau |
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| Affiliation: | 1. Department of Microbiology, Institute of Biology, Siedlce University of Natural Sciences and Humanities, Siedlce, Polandbarbara.kot@uph.edu.pl;3. Department of Microbiology, Institute of Biology, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland;4. Department of Agricultural Experimentation, Siedlce University of Natural Sciences and Humanities, Siedlce, Poland |
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| Abstract: | The aim of this study was to evaluate the ability of 0.1% thyme oil (TO), trans-cinnamaldehyde (TC), ferulic acid (FA), p-coumaric acid (p-CA), caffeic acid (CA), lavender essential oil (LO), geranium essential oil (GO) and tee tree oil (TTO) to control biofilms formed by methicillin-resistant Staphylococcus aureus (MRSA) strains. Depending on the strains, TO reduced 59.7–85% of biofilm mass, while TC 52.9–82.4% after 48 h of treatment. Reduction of metabolic activity of biofilms in ranges 79.3–86% and 85.9–88.7% was observed after 48 h of TC and TO of treatment, respectively. In the case of some strains, reduction of biofilm mass in the presence of FA, CA, GO, LO and TTO was not observed. This study showed that TO and TC might have therapeutic potential as an inhibitory agents for use in MRSA biofilm-related infections. |
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| Keywords: | Antibiofilm activity methicillin-resistant Staphylococcus aureus (MRSA) essential oils phytochemicals |
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