A convenient Baker yeast accelerated,one-pot synthesis of pentasubstituted thiopyridines |
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| Authors: | Anusaya S Chavan Arun S Kharat Manisha R Bhosle |
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| Institution: | 1. Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India;2. Department of Biotechnology, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad, India |
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| Abstract: | Here we report a novel Baker yeast catalyzed one pot cyclocondensation, performed at room temperature in ethanol for obtaining high yields of polyfunctionalized pyridines, 2-amino-4-aryl-3,5-dicyano-6-phenylthiopyridines. The developed protocol obeys certain green principles and is scalable and cost effective. |
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| Keywords: | 2-Amino-4-aryl-3 5-dicyano-6-phenylthiopyridines Baker yeast multicomponent reaction one pot |
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