Two new flavonoids from Artemisia argyi with their anticoagulation activities |
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Authors: | Jie-Li Lv Zhen-Zhen Li |
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Affiliation: | School of Pharmacy, Xinxiang Medical University, Xinxiang, People’s Republic of China |
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Abstract: | A new flavone glycoside, eupatilin 7-O-β-d-glucopyranoside (1) and a new flavone, 5,6,2′,4′-tetrahydroxy-7,5′-dimethoxyflavone (2), were isolated from Artemisia argyi. Their structures were unambiguously elucidated by extensive spectroscopic analysis. Both flavonoids were evaluated for in vitro anticoagulation activities. Compound 1 significantly extended thrombin time. Compound 2 had obvious effect in increasing prothrombin time. |
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Keywords: | Artemisia argyi Compositae flavone anticoagulation activity |
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