Lamesticumin G,a new α-glucosidase inhibitor from the fruit peels of Lansium parasiticum |
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| Authors: | Thammatee Potipiranun Wisuttaya Worawalai |
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| Institution: | 1. Faculty of Science, Program of Biotechnology, Chulalongkorn University, Bangkok, Thailand;2. Faculty of Science, Natural Products Research Unit, Department of Chemistry, Chulalongkorn University, Bangkok, Thailand;3. Faculty of Science, Natural Products Research Unit, Department of Chemistry, Chulalongkorn University, Bangkok, Thailand |
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| Abstract: | A novel onoceranoid triterpene, named lamesticumin G (1) along with four known compounds (2–5) were isolated from the ethyl acetate extract of the fruit peels of Lansium parasiticum. The structure of lamesticumin G (1) was fully characterised using spectroscopic data. Lamesticumin G (1) inhibited α-glucosidase (maltase) with IC50 value of 2.27 mM, while 2–5 showed no inhibition. |
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| Keywords: | Lamesticumin G Lansium parasiticum Meliaceae triterpenoid α-glucosidase onoceranoid diabetes |
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