| Sesquiterpenes and prenylated C_6–C_3 compounds from the stems of Illicium henryi |
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| 引用本文： | Peng-Yu Zhuang,Gui-Jie Zhang,Xiao-Jing Wang,Yan Zhang,Shi-Shan Yu. Sesquiterpenes and prenylated C_6–C_3 compounds from the stems of Illicium henryi[J]. 中国化学快报, 2015, 26(12): 1538-1541. DOI: 10.1016/j.cclet.2015.09.007 |
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| 作者姓名： | Peng-Yu Zhuang Gui-Jie Zhang Xiao-Jing Wang Yan Zhang Shi-Shan Yu |
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| 作者单位： | State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China |
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| 基金项目： | This project was supported by the Natural Science Foundation of China (No. 21132009) and the National Science and Technology Project of China (No. 2012ZX09301002-002). |
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| 摘 要： | One new sesquiterpene compound, namely, illihenlactone A(1), and one new prenylated C_6–C_3 compound, illihenryione H(2), along with three known sesquiterpenes(3–5) were isolated from the stems of Illicium henryi. The structures of 1 and 2 were elucidated by spectroscopic evidence including NMR, HRESIMS and circular dichroism(CD). Compound 2 exhibited a weak inhibitory ratio for bglucuronidase release induced by platelet-activating factor(PAF) in rat polymorphonuclear leukocytes(PMNs) in vitro.
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Sesquiterpenes and prenylated C6-C3 compounds from the stems of Illicium henryi |
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| Peng-Yu Zhuang,Gui-Jie Zhang,Xiao-Jing Wang,Yan Zhang,Shi-Shan Yu. Sesquiterpenes and prenylated C6-C3 compounds from the stems of Illicium henryi[J]. Chinese Chemical Letters, 2015, 26(12): 1538-1541. DOI: 10.1016/j.cclet.2015.09.007 |
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| Authors: | Peng-Yu Zhuang Gui-Jie Zhang Xiao-Jing Wang Yan Zhang Shi-Shan Yu |
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| Affiliation: | State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China |
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| Abstract: | One new sesquiterpene compound, namely, illihenlactone A (1), and one new prenylated C6-C3 compound, illihenryione H (2), along with three known sesquiterpenes (3-5) were isolated from the stems of Illicium henryi. The structures of 1 and 2 were elucidated by spectroscopic evidence including NMR, HRESIMS and circular dichroism (CD). Compound 2 exhibited a weak inhibitory ratio for β-glucuronidase release induced by platelet-activating factor (PAF) in rat polymorphonuclear leukocytes (PMNs) in vitro. |
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| Keywords: | Illicium henryi Sesquiterpene Prenylated C6-C3 compound Illihenryione H |
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