Synthesis of Indole Derivatives Attached to Polyethylene Oxides) |
| |
| Authors: | Ben-Zion Weiner Albert Zilkha |
| |
| Institution: | 1. Department of Organic Chemistry , The Hebrew University of Jerusalem Jerusalem , Israel;2. Teva Industries, Ltd. , Jerusalem, Israel;3. Department of Organic Chemistry , The Hebrew University of Jerusalem Jerusalem , Israel |
| |
| Abstract: | N-Benzyl 5-, 6-, and 7-bromoindolines were converted to the respective organosodium derivatives and used as initiators for the anionic polymerization of ethylene oxide. The resulting indoline derivatives attached to polyethylene oxide were dehydrogenated to the indole derivatives, which in turn were converted through suitable reactions to the tryptamine and indole acetic acid derivatives. |
| |
| Keywords: | |
|
|
