| SYNTHESIS AND DRUG RELEASE OF CROSSLINKING POLYPHOSPHATES |
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| 引用本文： | Luo Yi, Zhuo Renxi, Fan Changlie (Department of Chemistry,Wuhan University,Wuhan 430072). SYNTHESIS AND DRUG RELEASE OF CROSSLINKING POLYPHOSPHATES[J]. Chinese Journal of Reactive Polymers, 1995, 0(Z1) |
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| 作者姓名： | Luo Yi Zhuo Renxi Fan Changlie (Department of Chemistry Wuhan University Wuhan 430072) |
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| 作者单位： | Department of Chemistry，Wuhan University，Wuhan 430072 |
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| 摘 要： | ＳＹＮＴＨＥＳＩＳＡＮＤＤＲＵＧＲＥＬＥＡＳＥＯＦＣＲＯＳＳＬＩＮＫＩＮＧＰＯＬＹＰＨＯＳＰＨＡＴＥＳＬｕｏＹｉ；ＺｈｕｏＲｅｎｘｉ；ＦａｎＣｈａｎｇｌｉｅ（ＤｅｐａｒｔｍｅｎｔｏｆＣｈｅｍｉｓｔｒｙ，ＷｕｈａｎＵｎｉｖｅｒｓｉｔｙ，Ｗｕｈａｎ４３０...
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SYNTHESIS AND DRUG RELEASE OF CROSSLINKING POLYPHOSPHATES |
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| Luo Yi, Zhuo Renxi, Fan Changlie. SYNTHESIS AND DRUG RELEASE OF CROSSLINKING POLYPHOSPHATES[J]. 离子交换与吸附(英文版), 1995, 0(Z1) |
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| Authors: | Luo Yi Zhuo Renxi Fan Changlie |
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| Abstract: | A new class of crosslinking polyphosphates were synthesized characterizedby IR 1HNMR, 31PNMR spectroscopy as well as elemental analysis. In vitrodegradation of the polyphosphates obtained and the release of antineoplastic drugMethotrexate (MTX) and contraceptive Levonorgestrel (LNG ) by nsing thesepolymers as matrix were studied. Zero order release rate was rkserved in the case ofLNG release. |
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| Keywords: | Crosslinking polyphosphate Methotrexate Levonorgestrel Drug release |
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