Effects of nonionic sugar surfactants on the phase transition of DPPC membranes |
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| Authors: | Bo?enna Ró ?ycka-Roszak,Beata Jurczak |
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| Affiliation: | a Agricultural University, Department of Physics and Biophysics, Norwida 25, 50-375 Wroc?aw, Poland
b Wroclaw University of Technology, Department of Chemistry, Wybrze?e Wyspiańskiego 27, 50-370 Wroc?aw, Poland |
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| Abstract: | The influence of newly synthesized N-alkanoyl-N-methyllactitolamines (decanoyl [C10MELA], lauoroyl [C12MELA] and miristoyl [C14MELA]) on the thermotropic phase transition of phosphatidylcholine bilayer was compared with common sugar-based surfactants N-dodecyl-β-d-glucopyranoside [C12G1] and decanoyl-N-methyl glucamide [MEGA-10]. The results indicate that CnMELA are very active at the membrane surface and disturb the phospholipid bilayer structure less than commercially used MEGA-10 and C12G1. |
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| Keywords: | Nonionic sugar surfactants DPPC membrane DSC Phase transition |
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