An enantioselective synthetic route to cis-2,4-disubstituted and 2,4-bridged piperidines |
| |
| Authors: | Amat Mercedes Pérez Maria Minaglia Annamaria T Bosch Joan |
| |
| Affiliation: | Laboratory of Organic Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain. amat@ub.edu |
| |
| Abstract: | A synthetic route to enantiopure cis-2,4-disubstituted and 2,4-bridged piperidines is reported, the key step being a stereoselective conjugate addition of an organocuprate to a phenylglycinol-derived unsaturated lactam bearing a substituent at the 8a-position. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
