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Synthesis of Highly Functionalized Isoxazolinediones from One-pot Reaction of Alkylidene Meldrum ’s Acid with Alkyl Isocyanides in the Presence of Arylhydroxylamines |
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| Authors: | Azizollah Habibi Leyla Mousavifar Issa Yavari and Mohammad R Yazdanbakhsh |
| Institution: | (1) Key Laboratory of Acoustic and Photonic Materials and Devices of Ministry of Education, Wuhan University, 430072 Wuhan, People’s Republic of China;(2) Department of Physics, Wuhan University, 430072 Wuhan, People’s Republic of China;(3) Center of Electron Microscopy, Wuhan University, 430072 Wuhan, People’s Republic of China; |
| Abstract: | Alkyl isocyanides undergo a smooth reaction with alkylidene Meldrum’s acids in the presence of arylhydroxylamines to produce N 1-alkyl-2-(3,5-dioxo-2-aryltetrahydro-4-isoxazolyl)alkanamides in high yields. |
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