Copper-catalyzed synthesis of phenols from aryl halides and 4-methoxylbenzyl alcohol |
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| Authors: | Chuan Zhou Tao Wei Wei Liu Ji You Suna a |
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| Affiliation: | a Department of Chemical Engineering, Huaihai Institute of Technology, Lianyungang 222005, China;b Jiangsu Marine Resources R & D Institute, Lianyungang 222005, China |
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| Abstract: | A catalytic method was developed to synthesize substituted phenols from the corresponding aryl bromides and chlorides under mild conditions (yields = 34–92%). 4-Methoxylbenzyl alcohol was used as water surrogate and CuI/3,4,7,8-tetramethyl-1,10-phenanthroline was used as catalyst to achieve the C–O cross-coupling. |
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| Keywords: | Copper catalysis Water surrogate Cross-coupling Phenols |
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