The evaluation of measurement uncertainty from method validation studies |
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Authors: | Vicki J Barwick Stephen L R Ellison |
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Institution: | (1) Laboratory of the Government Chemist, Queens Road, Teddington, Middlesex, TW11 0LY, UK e-mail: vjb@lgc.co.uk Tel.: +44-20-89437421 Fax: +44-20-89432767, GB |
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Abstract: | A protocol has been developed illustrating the link between validation experiments, such as precision, trueness and ruggedness
testing, and measurement uncertainty evaluation. By planning validation experiments with uncertainty estimation in mind, uncertainty
budgets can be obtained from validation data with little additional effort. The main stages in the uncertainty estimation
process are described, and the use of trueness and ruggedness studies is discussed in detail. The practical application of
the protocol will be illustrated in Part 2, with reference to a method for the determination of three markers (CI solvent
red 24, quinizarin and CI solvent yellow 124) in fuel oil samples.
Received: 10 April 1999 / Accepted: 24 September 1999 |
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Keywords: | Measurement uncertainty Method validation Precision Trueness Ruggedness testing |
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