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13α-Hydroxymethylenedeacetyllaurenobiolide, a New Germacranolide from Tanacetopsis mucronata
Authors:B. Tashkhodzhaev  B. Kh. Abduazimov  M. B. Izbosarov  I. D. Sham'yanov  M. Yu. Antipin
Affiliation:(1) S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent;(2) Tashkent Pharmaceutical Institute, pr. Aibeka, 45;(3) Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent;(4) Institute of Element-Organic Compounds, Russian Academy of Sciences, Moscow, 117813, ul. Vavilova 28
Abstract:The new sesquiterpene lactone 13-hydroxymethylenedeacetyllaurenobiolide was isolated from the aerial part of Tanacetopsis mucronata S. Koval. (Asteraceae). Its structure was established using spectral data and X-ray structure analysis. The germacranolide macrocycle has the chair-chair conformation with the configuration 1D14, 15D5.
Keywords:Tanacetopsis mucronata  sesquiterpene lactone  13-hydroxymethylenedeacetyllaurenobiolide  X-ray structure analysis
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