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Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice
Authors:Lihua Li  Hua Zhang  AS Verkman
Affiliation:(1) Departments of Medicine and Physiology, University of California, San Francisco, California, USA
Abstract:

Background  

The involvement of astrocyte water channel aquaporin-4 (AQP4) in autoimmune diseases of the central nervous system has been suggested following the identification of AQP4 autoantibodies in neuromyelitis optica, an inflammatory demyelinating disease.
Keywords:
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