| 7-位取代的甾体类化合物生物活性研究进展 |
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| 引用本文： | 陈华龙,刘钦洲,黄燕敏,崔建国,陈小凤,甘春芳. 7-位取代的甾体类化合物生物活性研究进展[J]. 化学通报, 2022, 85(4): 446-451 |
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| 作者姓名： | 陈华龙 刘钦洲 黄燕敏 崔建国 陈小凤 甘春芳 |
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| 作者单位： | 广西天然高分子化学与物理重点实验室 南宁师范大学化学与材料学院 南宁 530001 |
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| 基金项目： | 国家自然科学基金项目（21762008），广西研究生教育创新计划资助项目(YCSW2021276)资助 |
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| 摘 要： | 7-位取代的甾体类化合物是一类具有良好生物活性的化合物,在抗炎、抗肿瘤等领域发挥着重要作用.本文以7-位取代的甾体类化合物为研究对象,按照不同的留体母核进行分类,对近年来有关7-位取代的甾体类化合物的生理活性研究进行综述,并为此类化合物的发展趋势和应用作了展望,以期为抗肿瘤药物的研发提供一定的理论基础.
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| 关 键 词： | 甾体 7-取代 抗肿瘤 生物活性 |
| 收稿时间： | 2021-08-04 |
| 修稿时间： | 2021-08-22 |
Research Progress on biological activities of 7-substituted steroids |
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| chen hualong,Liu Qinzhou,Huang Yanmin,Cui Jianguo,Chen Xiaofeng and Gan Chunfang. Research Progress on biological activities of 7-substituted steroids[J]. Chemistry, 2022, 85(4): 446-451 |
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| Authors: | chen hualong Liu Qinzhou Huang Yanmin Cui Jianguo Chen Xiaofeng Gan Chunfang |
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| Affiliation: | Nanning Normal University,Nanning Normal University,Nanning Normal University,Nanning Normal University,Nanning Normal University,Nanning Normal University |
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| Abstract: | The 7-substituted steroid compound is a compound with good biological activities and plays an important role in anti-inflammatory, anti-tumor and other fields. In this paper, the physiological activities of 7-substituted steroids in recent years were discussed, and the development trend and application of 7-substituted steroids were prospected. This paper may provide a theoretical basis for the development of antitumor drugs. |
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| Keywords: | steroidal 7-substituted antitumor bioactivity |
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