| 基因兴奋剂检测的现状与策略 |
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| 引用本文： | 何坚刚,刘震,刘晶,窦鹏,陈洪渊. 基因兴奋剂检测的现状与策略[J]. 色谱, 2008, 26(4): 402-407 |
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| 作者姓名： | 何坚刚 刘震 刘晶 窦鹏 陈洪渊 |
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| 作者单位： | Key Lab of Analytical Chemistry for Life Science, Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China |
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| 基金项目： | 国家自然科学基金科技奥运重点项目 , 国家自然科学基金面上项目 |
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| 摘 要： | 本文综述了基因兴奋剂检测的现状和反基因兴奋剂的策略。归纳了可能被运动员滥用的基因兴奋剂,分析了由这些基因表达的促红细胞生成素(EPO)、人生长激素(hGH)等蛋白的检测进展,讨论了未来检测基因兴奋剂的可能策略。
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| 关 键 词： | 基因兴奋剂 检测 重组蛋白 综述 |
| 收稿时间： | 2008-01-05 |
| 修稿时间： | 2008-07-30 |
Advances and strategies in gene doping detection |
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| HE Jiangang,LIU Zhen,LIU Jing,DOU Peng,CHEN Hong-Yuan. Advances and strategies in gene doping detection[J]. Chinese journal of chromatography, 2008, 26(4): 402-407 |
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| Authors: | HE Jiangang LIU Zhen LIU Jing DOU Peng CHEN Hong-Yuan |
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| Affiliation: | Key Lab of Analytical Chemistry for Life Science, Ministry of Education, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China |
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| Abstract: | This review surveys the recent status of gene doping detection and the strategies for anti-gene doping. The main gene doping candidates for athletes are summarized, and the advances in the detection of the proteins expressed by these genes such as erythropoietin (EPO) and human growth hormone (hGH) are reviewed. The potential detection strategies for further gene doping analysis are also discussed. |
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| Keywords: | gene doping recombinant proteins detection review |
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