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Synthesis and Fungicidal Activities of 2-Alkylthio-5-(3,4,5-tribenzyloxyphenyl)-l, 3,4-oxadiazoles
引用本文:De Qing LONG,De Jiang LI,Wei Quan CAI,Sheng Sheng CHEN Department of Chemistry,Yunyang Teachers College,Hubei 442700 College of Chemical Engineering,Wuhan University of Technology,Wuhan 430070. Synthesis and Fungicidal Activities of 2-Alkylthio-5-(3,4,5-tribenzyloxyphenyl)-l, 3,4-oxadiazoles[J]. 中国化学快报, 2006, 0(11)
作者姓名:De Qing LONG  De Jiang LI  Wei Quan CAI  Sheng Sheng CHEN Department of Chemistry  Yunyang Teachers College  Hubei 442700 College of Chemical Engineering  Wuhan University of Technology  Wuhan 430070
作者单位:De Qing LONG,De Jiang LI,Wei Quan CAI,Sheng Sheng CHEN Department of Chemistry,Yunyang Teachers College,Hubei 442700 College of Chemical Engineering,Wuhan University of Technology,Wuhan 430070
摘    要:Ten novel 2-alkylthio-5-(3, 4, 5-tribenzyloxyphenyl)-1, 3, 4-oxadiazole derivatives (5a-j) were synthesized from methyl 3, 4, 5-trihydroxybenzoate by etherification, hydrazidation, cyclization and thioetherification reactions. The structures of 5a-j were confirmed by 1HNMR, MS spectra and elemental analysis. The results indicated that most of the compounds 5 exhibited good fungicidal activities. The activity of 5h is higher than 90% against Fusarium oxysporum and Botrytis cinereapers in 50 mg/L.


Synthesis and Fungicidal Activities of 2-Alkylthio-5-(3,4,5-tribenzyloxyphenyl)-l, 3,4-oxadiazoles
De Qing LONG,De Jiang LI,Wei Quan CAI,Sheng Sheng CHEN. Synthesis and Fungicidal Activities of 2-Alkylthio-5-(3,4,5-tribenzyloxyphenyl)-l, 3,4-oxadiazoles[J]. Chinese Chemical Letters, 2006, 0(11)
Authors:De Qing LONG  De Jiang LI  Wei Quan CAI  Sheng Sheng CHEN
Affiliation:De Qing LONG,De Jiang LI,Wei Quan CAI,Sheng Sheng CHEN Department of Chemistry,Yunyang Teachers College,Hubei 442700 College of Chemical Engineering,Wuhan University of Technology,Wuhan 430070
Abstract:Ten novel 2-alkylthio-5-(3, 4, 5-tribenzyloxyphenyl)-1, 3, 4-oxadiazole derivatives (5a-j) were synthesized from methyl 3, 4, 5-trihydroxybenzoate by etherification, hydrazidation, cyclization and thioetherification reactions. The structures of 5a-j were confirmed by 1HNMR, MS spectra and elemental analysis. The results indicated that most of the compounds 5 exhibited good fungicidal activities. The activity of 5h is higher than 90% against Fusarium oxysporum and Botrytis cinereapers in 50 mg/L.
Keywords:1   3   4-Oxadiazole derivatives   synthesis   fungicidal activity
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