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Total synthesis of debromoflustramine B via biomimetic alkylative cyclization |
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| Authors: | Tan Gan Hup Zhu Xiuwen Ganesan A |
| Institution: | Department of Chemistry, University of Southampton, Southampton SO17 1BJ, United Kingdom. |
| Abstract: | reaction: see text] The hexahydropyrrolo2,3-b]indoline skeleton is readily accessed by the zinc triflate-mediated alkylation of tryptamine derivatives. The methodology was employed in a three-step total synthesis of debromoflustramine B. |
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