Combined carbometalation-zinc homologation-allylation reactions as a new approach for alkoxyallylation of aldehydes |
| |
| Authors: | Mejuch Tom Botoshansky Mark Marek Ilan |
| |
| Institution: | The Mallat Family Laboratory of Organic Chemistry, Schulich Faculty of Chemistry and the Lise Meitner-Minerva Center for Computational Quantum Chemistry, Technion-Israel Institute of Technology, Technion City, Haifa 32000, Israel. |
| |
| Abstract: | The combined carbometalation reaction of ynol ethers followed by a zinc homologation and further allylation reactions lead to an efficient preparation of allylic vicinal diols. The stereochemical outcome of the reaction shows that the substituent of the aldehyde occupies a pseudoaxial position in a Zimmerman-Traxler transition state. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
