Synthesis and Alkylation of N-Methylmorpholinium 4-Aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydro-2-pyridinethiolates. Molecular and Crystal Structure of 4,5-trans-3,5-Dicyano-4-(2-methoxyphenyl)-2-methylthio-6-oxo-1,4,5,6-tetrahydropyridine |
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| Authors: | S. G. Krivokolysko V. D. Dyachenko E. B. Rusanov V. P. Litvinov |
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| Affiliation: | (1) Taras Shevchenko Lugansk State Pedagogical University, 348011 Lugansk, Ukraine;(2) Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 253660 Kiev;(3) N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow, Russia |
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| Abstract: | The reaction of aromatic aldehydes with cyanothioacetamide and ethyl cyanoacetate in the presence of N-methylmorpholine gives N-methylmorpholinium 4-aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydro-2-pyridinethiolates, which are used in the synthesis of substituted 2-alkylthiotetrahydropyridines. X-ray diffraction analysis was used to study the structure of 4,5-trans-3,5-dicyano-4-(2-methoxyphenyl)-2-methylthio-6-oxo-1,4,5,6-tetrahydropyridine. |
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| Keywords: | aromatic aldehydes substituted N-methylmorpholinium 1,4,5,6-tetrahydro-2-pyridinethiolates cyanothioacetamide ethyl cyanoacetate X-ray diffraction analysis |
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